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[9] Stanbrook, M.B., et al

In this case, 22nd Century Group wanted to state that each of its products contains 95 percent less nicotine, helps reduce your nicotine consumption and VLN smells, burns and tastes like a conventional cigarette but greatly reduces your nicotine consumption. They provided the scientific evidence to back up those claims

Cigarettes had been widely used in the United States for decades before conclusive evidence of the link between their use and premature death from cancer and cardiac events was established in the 1950s and early 1960s

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